Immune Escape And Response To Immunotherapy
by
Natalia Aptsiauri, Angel Miguel Garcia-Lora, Teresa Cabrera
Language: English
Release Date: February 26, 2013
Abnormal expression of MHC class I molecules in malignant cells is a frequent occurrence that ranges from total loss of all class I antigens to partial loss of MHC specific haplotypes or alleles. Different mechanisms are described to be responsible for these alterations, requiring different therapeutic...