Pharmacy category: 507 books

Cover of Phase II Clinical Development of New Drugs
by Ding-Geng Chen, Joseph C. Cappelleri, Naitee Ting
Language: English
Release Date: April 8, 2017

This book focuses on how to appropriately plan and develop a Phase II program, and how to design Phase II clinical trials and analyze their data. It provides a comprehensive overview of the entire drug development process and highlights key questions that need to be addressed for the successful execution...
Cover of Biosimulation in Biomedical Research, Health Care and Drug Development
by
Language: English
Release Date: November 1, 2011

Biosimulation is an approach to biomedical research and the treatment of patients in which computer modeling goes hand in hand with experimental and clinical work. Constructed models are used to interpret experimental results and to accumulate information from experiment to experiment. This...
Cover of Antibiotic Pharmacokinetic/Pharmacodynamic Considerations in the Critically Ill
by
Language: English
Release Date: September 18, 2017

This book provides unique insights into the issues that drive modified dosing regimens for antibiotics in the critically ill. Leading international authors provide their commentary alongside a summary of existing evidence on how to effectively dose antibiotics. Severe infection frequently necessitates...
Cover of Pharmacologic Therapy of Ocular Disease
by
Language: English
Release Date: June 5, 2017

There have been major advancements in the pharmacologic treatment of eye diseases over the past decade. With newly discovered disease targets and novel approaches to deliver therapeutic compounds to the eye, patients are seeing improved outcomes. Not only are there better treatments for diseases...
Cover of Sample Preparation of Pharmaceutical Dosage Forms

Sample Preparation of Pharmaceutical Dosage Forms

Challenges and Strategies for Sample Preparation and Extraction

by
Language: English
Release Date: August 5, 2011

This book is intended to serve as a resource for analysts in developing and troubleshooting sample preparation methods.  These are critical activities in providing accurate and reliable data throughout the lifecycle of a drug product.  This book is divided into four parts: •         ...
Cover of Drug Delivery to the Brain

Drug Delivery to the Brain

Physiological Concepts, Methodologies and Approaches

by
Language: English
Release Date: December 3, 2013

The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood –brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/passive...
Cover of Toxicology of Herbal Products
by
Language: English
Release Date: March 7, 2017

This volume provides a comprehensive overview of the hazards inherent in herbal medicinal products, with systematic coverage of major toxicities. Topics include composition and quality control, toxicokinetics, interactions, safety pharmacology, approaches to studying complex mixtures including metabolomics...
Cover of Incorporation of Heterocycles into Combinatorial Chemistry
by Eugene V. Babaev
Language: English
Release Date: December 1, 2016

The author has summarized a decade of teaching combinatorial chemistry into this timely brief. The solid phase synthesis of unnatural heterocyclic alpha-amino acids is illustrated by practical examples starting from the ABCs of peptide synthesis explored in chapter one. Chapter two is concerned with...
Cover of Electroanalysis in Biomedical and Pharmaceutical Sciences

Electroanalysis in Biomedical and Pharmaceutical Sciences

Voltammetry, Amperometry, Biosensors, Applications

by Sibel A. Ozkan, Jean-Michel Kauffmann, Petr Zuman
Language: English
Release Date: July 8, 2015

Through this monograph, the pharmaceutical chemist gets familiar with the possibilities electroanalytical methods offer for validated analyses of drug compounds and pharmaceuticals. The presentation focuses on the techniques most frequently used in practical applications, particularly voltammetry...
Cover of Natural Products in the Chemical Industry
by Bernd Schaefer
Language: English
Release Date: May 26, 2015

Natural Products in the Chemical Industry is not a conventional textbook, but rather an invitation to join an entertaining journey that takes you into the fascinating world of natural products. This book features diverse compound classes from a number of areas: colour­ants, fragrances and flavourings,...
Cover of Targeted Drug Delivery : Concepts and Design
by
Language: English
Release Date: December 8, 2014

This authoritative volume explores the fundamental concepts and numerous applications of targeted delivery of drugs to the body. This compilation has been divided into eight sections comprised of the basic principles of drug targeting, disease and organ/organelle-based targeting, passive and active...
Cover of Oral Mucosal Drug Delivery and Therapy
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Language: English
Release Date: March 13, 2015

This volume provides a comprehensive overview of the current issues facing scientists working on delivering drugs locally and systemically via the membranes that line the mouth. The book describes the anatomical and physiological challenges of this route for drug delivery and how they impact the design...
Cover of Rubidomycin

Rubidomycin

A New Agent against Cancer

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Language: English
Release Date: December 6, 2012

Trials in the treatment of the leukemias are sometimes based on a hypothesis, as in the case of exchange transfusion [33] or the use of antimetabolites [86]. Or they are conducted empirically as the results of chance observations, as in the case of the use of the nitrogen mustards, urethane, and the...
Cover of Good Cascade Impactor Practices, AIM and EDA for Orally Inhaled Products
by
Language: English
Release Date: April 10, 2013

The purpose of this publication is to introduce a new, simpler and more effective way in which to interpret pharmaceutical aerosol particle size data from orally inhaled products (OIPs). Currently, the compendial and regulatory requirements dictate the need for measurements by full resolution multi-stage...
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