Molecular Biology category: 1516 books

Cover of Mesenchymal Stem Cells and Immunomodulation
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Language: English
Release Date: December 10, 2016

This essential volume explores mesenchymal stem cells (MSCs) and their potential to suppress immune-mediated inflammation. The chapters examine applications in autoimmune diseases such as lupus, rheumatoid arthritis and multiple sclerosis; blood cancers such as leukemia and lymphoma; and reproductive...
Cover of ABC Proteins

ABC Proteins

From Bacteria to Man

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Language: English
Release Date: January 7, 2003

ABC Proteins is an in-depth, up-to-date analysis of all that is known about the subject to date. It discusses and compares evolution, biology and mechanism of action of all known ABC proteins, including the first structural studies as well as clinical implications. It will be useful to anyone trying...
Cover of Epigenomics in Health and Disease
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Language: English
Release Date: October 12, 2015

Epigenomics in Health and Disease discusses the next generation sequencing technologies shaping our current knowledge with regards to the role of epigenetics in normal development, aging, and disease. It includes the consequences for diagnostics, prognostics, and disease-based therapies made...
Cover of Nuclear Receptors

Nuclear Receptors

Current Concepts and Future Challenges

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Language: English
Release Date: March 11, 2010

In 1890 a case of myxedema was treated in Lisbon by the implantation of a sheep thyroid gland with the immediate improvement in the patient’s condition. A few years later, medications for the then ill-explained condition of the menopause included tablets made from cow ovaries. In the first quarter...
Cover of Organisation of Chromosomes
by Rossen Donev
Language: English
Release Date: April 5, 2013

Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology serial has been a continuous, essential resource for protein chemists. Covering reviews of methodology and research in all aspects of protein chemistry, including purification/expression, proteomics, modeling...
Cover of Fe-S Cluster Enzymes Part B
by Sheila S. David
Language: English
Release Date: January 20, 2018

Methods in Enzymology, Volume 599 is the second of two volumes focused on Fe-S cluster enzymes. Topics of interest in this new release include steps towards understanding mitochondrial Fe/S cluster biogenesis, iron sulfur clusters in zinc finger proteins, electrochemistry of Iron-sulfur enzymes, NRVS...
Cover of Biophysics of DNA-Protein Interactions

Biophysics of DNA-Protein Interactions

From Single Molecules to Biological Systems

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Language: English
Release Date: October 5, 2010

Depite the rapid expansion of the field of biophysics, there are very few books that comprehensively treat specific topics in this area. Recently, the field of single molecule biophysics has developed very quickly, and a few books specifically treating single molecule methods are beginning to appear....
Cover of Hypoxia and Cancer

Hypoxia and Cancer

Biological Implications and Therapeutic Opportunities

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Language: English
Release Date: November 9, 2013

​​​The imbalance between rapidly proliferating tumor cells and inadequate and inefficient tumor vasculature leads to a decrease in oxygen levels (hypoxia and/or anoxia) in tumor tissues. Intra-tumor hypoxia profoundly affects the biological behavior of cancer cells, which become resistant to...
Cover of Cellular Peptide Hormone Synthesis and Secretory Pathways
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Language: English
Release Date: March 10, 2010

The concept of hormonal regulation using intercellular peptide messengers dates back to the discovery of secretin in 1902. The concept was simple: A peptide is released from specific hormone producing cells, endocrine cells, into circulation upon stimulation of the cells. The peptide hormone travels...
Cover of Molecules to Medicine with mTOR

Molecules to Medicine with mTOR

Translating Critical Pathways into Novel Therapeutic Strategies

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Language: English
Release Date: February 21, 2016

Molecules to Medicine with mTOR: Translating Critical Pathways into Novel Therapeutic Strategies is a one-stop reference that thoroughly covers the mechanistic target of rapamycin (mTOR). mTOR, also known as the mammalian target of rapamycin, is a 289-kDa serine/threonine protein kinase that is ubiquitous...
Cover of Bioinformatics for Diagnosis, Prognosis and Treatment of Complex Diseases
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Language: English
Release Date: November 25, 2013

The book introduces the bioinformatics tools, databases and strategies for the translational research, focuses on the biomarker discovery based on integrative data analysis and systems biological network reconstruction. With the coming of personal genomics era, the biomedical data will be accumulated...
Cover of Male Germline Stem Cells: Developmental and Regenerative Potential
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Language: English
Release Date: December 16, 2010

Scientists investigating germ cells have, over the past 15 years, originated discoveries and innovations that give us valuable insights into the mechanisms that regulate not just stem cell function, but human development in its widest sense. With contributions from some of the leading researchers...
Cover of Gap Junction Channels and Hemichannels
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Language: English
Release Date: August 5, 2016

Gap junction channels are a group of intercellular channels expressed in tissues and organs to synchronize many physiological processes. A gap junction channel is formed by the docking of two hemichannels, and each hemichannel is a hexamer of connexins. The field of gap junction channel and hemichannel...
Cover of Phosphorescent Oxygen-Sensitive Probes
by Dmitri Papkovsky, Alexander V. Zhdanov, Andreas Fercher
Language: English
Release Date: August 31, 2012

Biological O2 sensing probes and measurement techniques were first introduced in the late 80s. In the last 3-5 years they have undergone major development that have made them available and affordable for a broad range of applications in various disciplines of the life and biomedical sciences. These...
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