Autophagy Networks in Inflammation

Nonfiction, Health & Well Being, Medical, Medical Science, Immunology, Science & Nature, Science, Other Sciences, Molecular Biology
Cover of the book Autophagy Networks in Inflammation by , Springer International Publishing
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9783319300795
Publisher: Springer International Publishing Publication: August 17, 2016
Imprint: Springer Language: English
Author:
ISBN: 9783319300795
Publisher: Springer International Publishing
Publication: August 17, 2016
Imprint: Springer
Language: English

Autophagy principally serves an adaptive function to protect organisms against diverse human pathologies, including cancer and neurodegeneration. Recent developments using in vitro, ex vivo and in vivo models show the involvement of the autophagy pathway in immunity and inflammation. Moreover, direct interactions between autophagy proteins and immune signalling molecules have also been demonstrated. Defects in autophagy - similar to cancer, neurodegenerative diseases and aging - through autophagy gene mutation and/or microbial antagonism, may underlie the pathogenesis of many infectious diseases and inflammatory syndromes. In spite of the increasing awareness of the importance of autophagy in these pathophysiological conditions, this process remains underestimated and is often overlooked. As a consequence, its role in the initiation, stability, maintenance, and progression of these diseases are still poorly understood. This book reviews the recent advances regarding the functions of the autophagy pathway and autophagy proteins in immunity and inflammation, focusing on their role in self-nonself distinction, their implications in innate and adaptive immune responses and their dysregulation in the pathology of certain inflammatory and autoimmune diseases.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Autophagy principally serves an adaptive function to protect organisms against diverse human pathologies, including cancer and neurodegeneration. Recent developments using in vitro, ex vivo and in vivo models show the involvement of the autophagy pathway in immunity and inflammation. Moreover, direct interactions between autophagy proteins and immune signalling molecules have also been demonstrated. Defects in autophagy - similar to cancer, neurodegenerative diseases and aging - through autophagy gene mutation and/or microbial antagonism, may underlie the pathogenesis of many infectious diseases and inflammatory syndromes. In spite of the increasing awareness of the importance of autophagy in these pathophysiological conditions, this process remains underestimated and is often overlooked. As a consequence, its role in the initiation, stability, maintenance, and progression of these diseases are still poorly understood. This book reviews the recent advances regarding the functions of the autophagy pathway and autophagy proteins in immunity and inflammation, focusing on their role in self-nonself distinction, their implications in innate and adaptive immune responses and their dysregulation in the pathology of certain inflammatory and autoimmune diseases.

More books from Springer International Publishing

Cover of the book Radon: A Tracer for Geological, Geophysical and Geochemical Studies by
Cover of the book The Palgrave Handbook of Urban Ethnography by
Cover of the book Rhetoric, Social Value and the Arts by
Cover of the book Software Technologies by
Cover of the book Landscape Ecology for Sustainable Society by
Cover of the book Cross-Cultural Design. Methods, Tools and User Experience by
Cover of the book Reconstruction, Identification and Implementation Methods for Spiking Neural Circuits by
Cover of the book A Mathematical Modeling Approach from Nonlinear Dynamics to Complex Systems by
Cover of the book Altruism, Welfare and the Law by
Cover of the book Challenges to African Entrepreneurship in the 21st Century by
Cover of the book Representation Theory by
Cover of the book Topics in Cryptology – CT-RSA 2018 by
Cover of the book The Rise and Fall of the Fifth Force by
Cover of the book Elements of Neurogeometry by
Cover of the book The Secular Landscape by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy