Asymmetric Synthesis of Bioactive Lactones and the Development of a Catalytic Asymmetric Synthesis of α-Aryl Ketones

Nonfiction, Science & Nature, Science, Chemistry, Technical & Industrial, Organic
Cover of the book Asymmetric Synthesis of Bioactive Lactones and the Development of a Catalytic Asymmetric Synthesis of α-Aryl Ketones by Robert Doran, Springer International Publishing
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Robert Doran ISBN: 9783319205441
Publisher: Springer International Publishing Publication: June 24, 2015
Imprint: Springer Language: English
Author: Robert Doran
ISBN: 9783319205441
Publisher: Springer International Publishing
Publication: June 24, 2015
Imprint: Springer
Language: English

This thesis addresses two fundamental areas in contemporary organic chemistry: synthesis of natural products and catalytic asymmetric synthesis. Firstly, a new methodology, developed by our research group, which allows the asymmetric synthesis of lactones, a structural unit ubiquitous in natural products, was utilised in the synthesis of a number of natural product analogues that showed significant biological activity. Secondly, the development of a catalytic asymmetric synthesis of a key structural motif present in a number of natural products and pharmaceuticals was accomplished. During the course of this work we discovered dual stereo control, which is significant because it allows the configuration of a new stereo centre to be controlled by a simple change of proton source.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

This thesis addresses two fundamental areas in contemporary organic chemistry: synthesis of natural products and catalytic asymmetric synthesis. Firstly, a new methodology, developed by our research group, which allows the asymmetric synthesis of lactones, a structural unit ubiquitous in natural products, was utilised in the synthesis of a number of natural product analogues that showed significant biological activity. Secondly, the development of a catalytic asymmetric synthesis of a key structural motif present in a number of natural products and pharmaceuticals was accomplished. During the course of this work we discovered dual stereo control, which is significant because it allows the configuration of a new stereo centre to be controlled by a simple change of proton source.

More books from Springer International Publishing

Cover of the book A Practical Approach to Adolescent Bone Health by Robert Doran
Cover of the book Democratic Representation in Plurinational States by Robert Doran
Cover of the book High Strain Rate Behavior of Nanocomposites and Nanocoatings by Robert Doran
Cover of the book Reconciling Islam, Christianity and Judaism by Robert Doran
Cover of the book Sex Workers and Criminalization in North America and China by Robert Doran
Cover of the book Radioguided Surgery by Robert Doran
Cover of the book Discrete and Computational Geometry and Graphs by Robert Doran
Cover of the book Optimization in Electrical Engineering by Robert Doran
Cover of the book Competition in Higher Education Branding and Marketing by Robert Doran
Cover of the book Revisiting Slavery and Antislavery by Robert Doran
Cover of the book Rapid Cell Magnetisation Using Cationised Magnetoferritin by Robert Doran
Cover of the book Growth and Characterization of Bulk Superconductor Material by Robert Doran
Cover of the book The Family Office by Robert Doran
Cover of the book Reviews of Environmental Contamination and Toxicology Volume 235 by Robert Doran
Cover of the book International Migration and Crisis by Robert Doran
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy