Aromatic Fluorination

Nonfiction, Science & Nature, Science, Chemistry, Organic
Cover of the book Aromatic Fluorination by James H. Clark, CRC Press
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: James H. Clark ISBN: 9781351086783
Publisher: CRC Press Publication: January 10, 2018
Imprint: CRC Press Language: English
Author: James H. Clark
ISBN: 9781351086783
Publisher: CRC Press
Publication: January 10, 2018
Imprint: CRC Press
Language: English

Academia and industry join forces in Aromatic Fluorination, as an expert from each domain contributes to this new text on fluorination of carbocyclic and heterocyclic rings. The book begins with a discussion of fluorine's unique combination of properties, including size, electronic effects, and hydrophobicity, as well as the historical development of its product applications. It explains methods for introducing fluorine into an aromatic ring, focusing on nucleophilic fluorine transfer reactions. The role of catalysts, solvents, and other variables are examined, and the scope and limitations of the methods are discussed. Of particular interest to those working in non-specialist laboratories, Aromatic Fluorination includes detailed descriptions of the new electrophilic routes to fluoroaromatics, in addition to traditional routes and alternative methods involving radical chemistry. Because one of the most important fluorine-containing substituent is CF3, the book explains routes to benzotrifluorides (ArCF3), including traditional industrial methods and modern alternatives employing C-1 halofluorocarbons and other fluoroaliphatics. An alternative to CF3 is CF3S, and several methods of synthesizing aromatic CF3S-containing molecules are described. Since the successful development and diverse applications of aromatic fluorine compounds have led to the search for new compounds and novel substituents, the incorporation of other substituents is also explored. Aromatic Fluorination concludes with discussion of the factors responsible for the successful development of pharmaceutical, agrochemical and liquid crystal applications and the potential for applications in high-performance polymers and other areas. This section also describes in detail important industrial aromatic fluorination processes and the relative merits of different process technologies and their costs.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Academia and industry join forces in Aromatic Fluorination, as an expert from each domain contributes to this new text on fluorination of carbocyclic and heterocyclic rings. The book begins with a discussion of fluorine's unique combination of properties, including size, electronic effects, and hydrophobicity, as well as the historical development of its product applications. It explains methods for introducing fluorine into an aromatic ring, focusing on nucleophilic fluorine transfer reactions. The role of catalysts, solvents, and other variables are examined, and the scope and limitations of the methods are discussed. Of particular interest to those working in non-specialist laboratories, Aromatic Fluorination includes detailed descriptions of the new electrophilic routes to fluoroaromatics, in addition to traditional routes and alternative methods involving radical chemistry. Because one of the most important fluorine-containing substituent is CF3, the book explains routes to benzotrifluorides (ArCF3), including traditional industrial methods and modern alternatives employing C-1 halofluorocarbons and other fluoroaliphatics. An alternative to CF3 is CF3S, and several methods of synthesizing aromatic CF3S-containing molecules are described. Since the successful development and diverse applications of aromatic fluorine compounds have led to the search for new compounds and novel substituents, the incorporation of other substituents is also explored. Aromatic Fluorination concludes with discussion of the factors responsible for the successful development of pharmaceutical, agrochemical and liquid crystal applications and the potential for applications in high-performance polymers and other areas. This section also describes in detail important industrial aromatic fluorination processes and the relative merits of different process technologies and their costs.

More books from CRC Press

Cover of the book Building and Using a Groundwater Database by James H. Clark
Cover of the book Sparse Optimization Theory and Methods by James H. Clark
Cover of the book Achieving Successful Construction Projects by James H. Clark
Cover of the book Ferroelectric Devices by James H. Clark
Cover of the book One World Health by James H. Clark
Cover of the book Lean Production for the Small Company by James H. Clark
Cover of the book Mathematics for Engineering by James H. Clark
Cover of the book Neuro-Fuzzy Equalizers for Mobile Cellular Channels by James H. Clark
Cover of the book Motorcycling and Leisure by James H. Clark
Cover of the book Introduction to Functional Data Analysis by James H. Clark
Cover of the book Life After Darkness by James H. Clark
Cover of the book 3D Art Essentials by James H. Clark
Cover of the book Stormwater Infiltration by James H. Clark
Cover of the book The Little Adsorption Book by James H. Clark
Cover of the book Statistical Methods in Agriculture and Experimental Biology by James H. Clark
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy