Advances in Protein Chemistry and Structural Biology

Nonfiction, Science & Nature, Science, Biological Sciences, Cytology, Other Sciences, Molecular Biology
Cover of the book Advances in Protein Chemistry and Structural Biology by Alexander McPherson, Elsevier Science
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Alexander McPherson ISBN: 9780123819635
Publisher: Elsevier Science Publication: September 9, 2010
Imprint: Academic Press Language: English
Author: Alexander McPherson
ISBN: 9780123819635
Publisher: Elsevier Science
Publication: September 9, 2010
Imprint: Academic Press
Language: English

Structural genomics is the systematic determination of 3-D structures of proteins representative of the range of protein structure and function found in nature. The goal is to build a body of structural information that will predict the structure and potential function for almost any protein from knowledge of its coding sequence. This is essential information for understanding the functioning of the human proteome, the ensemble of tens of thousands of proteins specified by the human genome.

While most structural biologists pursue structures of individual proteins or protein groups, specialists in structural genomics pursue structures of proteins on a genome wide scale. This implies large-scale cloning, expression and purification. One main advantage of this approach is economy of scale.

  • Examines the three dimensional structure of all proteins of a given organism, by experimental methods such as X-ray crystallography and NMR spectroscopy
  • Looks at structural genomics as a foundation of drug discovery as discovering new medicines is becoming more challenging and the pharmaceutical industry is looking to new technologies to help in this mission
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Structural genomics is the systematic determination of 3-D structures of proteins representative of the range of protein structure and function found in nature. The goal is to build a body of structural information that will predict the structure and potential function for almost any protein from knowledge of its coding sequence. This is essential information for understanding the functioning of the human proteome, the ensemble of tens of thousands of proteins specified by the human genome.

While most structural biologists pursue structures of individual proteins or protein groups, specialists in structural genomics pursue structures of proteins on a genome wide scale. This implies large-scale cloning, expression and purification. One main advantage of this approach is economy of scale.

More books from Elsevier Science

Cover of the book Principles of Tissue Engineering by Alexander McPherson
Cover of the book Equine-Facilitated Psychotherapy and Learning by Alexander McPherson
Cover of the book Elementary Linear Programming with Applications by Alexander McPherson
Cover of the book Myogenesis in Development and Disease by Alexander McPherson
Cover of the book Recent Progress in Hormone Research by Alexander McPherson
Cover of the book Working Guide to Vapor-Liquid Phase Equilibria Calculations by Alexander McPherson
Cover of the book Principles of Filtration by Alexander McPherson
Cover of the book Maintaining and Evolving Successful Commercial Web Sites by Alexander McPherson
Cover of the book Molecular Biology of Placental Development and Disease by Alexander McPherson
Cover of the book Management of Marine Plastic Debris by Alexander McPherson
Cover of the book Disorders of the Cervical Spine by Alexander McPherson
Cover of the book Molecular Diagnostics by Alexander McPherson
Cover of the book Corridors to Extinction and the Australian Megafauna by Alexander McPherson
Cover of the book Silicon-Germanium (SiGe) Nanostructures by Alexander McPherson
Cover of the book Parameter Identification and Monitoring of Mechanical Systems Under Nonlinear Vibration by Alexander McPherson
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy