Accelerated Path to Cures

Nonfiction, Health & Well Being, Medical, Medical Science, Immunology, Computers, Advanced Computing, Computer Science
Cover of the book Accelerated Path to Cures by , Springer International Publishing
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9783319732381
Publisher: Springer International Publishing Publication: April 25, 2018
Imprint: Springer Language: English
Author:
ISBN: 9783319732381
Publisher: Springer International Publishing
Publication: April 25, 2018
Imprint: Springer
Language: English

Accelerated Path to Cures provides a transformative perspective on the power of combining advanced computational technologies, modeling, bioinformatics and machine learning approaches with nonclinical and clinical experimentation to accelerate drug development. This book discusses the application of advanced modeling technologies, from target identification and validation to nonclinical studies in animals to Phase 1-3 human clinical trials and post-approval monitoring, as alternative models of drug development. As a case of successful integration of computational modeling and drug development, we discuss the development of oral small molecule therapeutics for inflammatory bowel disease, from the application of docking studies to screening new chemical entities to the development of next-generation in silico human clinical trials from large-scale clinical data. Additionally, this book illustrates how modeling techniques, machine learning, and informatics can be utilized effectively at each stage of drug development to advance the progress towards predictive, preventive, personalized, precision medicine, and thus provide a successful framework for Path to Cures. 

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Accelerated Path to Cures provides a transformative perspective on the power of combining advanced computational technologies, modeling, bioinformatics and machine learning approaches with nonclinical and clinical experimentation to accelerate drug development. This book discusses the application of advanced modeling technologies, from target identification and validation to nonclinical studies in animals to Phase 1-3 human clinical trials and post-approval monitoring, as alternative models of drug development. As a case of successful integration of computational modeling and drug development, we discuss the development of oral small molecule therapeutics for inflammatory bowel disease, from the application of docking studies to screening new chemical entities to the development of next-generation in silico human clinical trials from large-scale clinical data. Additionally, this book illustrates how modeling techniques, machine learning, and informatics can be utilized effectively at each stage of drug development to advance the progress towards predictive, preventive, personalized, precision medicine, and thus provide a successful framework for Path to Cures. 

More books from Springer International Publishing

Cover of the book Postcolonial Portuguese Migration to Angola by
Cover of the book Models and Methods for Interval-Valued Cooperative Games in Economic Management by
Cover of the book AI*IA 2018 – Advances in Artificial Intelligence by
Cover of the book Artificial Neural Networks and Machine Learning – ICANN 2016 by
Cover of the book Renewal Theory for Perturbed Random Walks and Similar Processes by
Cover of the book Advanced Information Systems Engineering Workshops by
Cover of the book Characterization of Minerals, Metals, and Materials 2017 by
Cover of the book Driving Demand for Broadband Networks and Services by
Cover of the book Education Policy and the Australian Education Union by
Cover of the book Mechanical Systems by
Cover of the book Climate Change-Resilient Agriculture and Agroforestry by
Cover of the book Interrogating the Neoliberal Lifecycle by
Cover of the book Scholars and Scholarship in Late Babylonian Uruk by
Cover of the book Sand and Gravel Spits by
Cover of the book The Strauss-Krüger Correspondence by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy