A Systems Biology Approach to Blood

Nonfiction, Health & Well Being, Medical, Specialties, Internal Medicine, Hematology, Science & Nature, Science, Biological Sciences
Cover of the book A Systems Biology Approach to Blood by , Springer New York
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9781493920952
Publisher: Springer New York Publication: December 6, 2014
Imprint: Springer Language: English
Author:
ISBN: 9781493920952
Publisher: Springer New York
Publication: December 6, 2014
Imprint: Springer
Language: English

The blood system is multi-scale, from the organism to the organs to cells to intracellular signaling pathways to macromolecule interactions. Blood consists of circulating cells, cellular fragments (platelets and microparticles), and plasma macromolecules. Blood cells and their fragments result from a highly-ordered process, hematopoiesis. Definitive hematopoiesis occurs in the bone marrow, where pluripotential stem cells give rise to multiple lineages of highly specialized cells. Highly-productive and continuously regenerative, hematopoiesis requires a microenvironment of mesenchymal cells and blood vessels.

A Systems Biology Approach to Blood is divided into three main sections: basic components, physiological processes, and clinical applications. Using blood as a window, one can study health and disease through this unique tool box with reactive biological fluids that mirrors the prevailing hemodynamics of the vessel walls and the various blood cell types. Many blood diseases, rare and common can and have been exploited using systems biology approaches with successful results and therefore ideal models for systems medicine. More importantly, hematopoiesis offers one of the best studied systems with insight into stem cell biology, cellular interaction, development; linage programing and reprograming that are every day influenced by the most mature and understood regulatory networks.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

The blood system is multi-scale, from the organism to the organs to cells to intracellular signaling pathways to macromolecule interactions. Blood consists of circulating cells, cellular fragments (platelets and microparticles), and plasma macromolecules. Blood cells and their fragments result from a highly-ordered process, hematopoiesis. Definitive hematopoiesis occurs in the bone marrow, where pluripotential stem cells give rise to multiple lineages of highly specialized cells. Highly-productive and continuously regenerative, hematopoiesis requires a microenvironment of mesenchymal cells and blood vessels.

A Systems Biology Approach to Blood is divided into three main sections: basic components, physiological processes, and clinical applications. Using blood as a window, one can study health and disease through this unique tool box with reactive biological fluids that mirrors the prevailing hemodynamics of the vessel walls and the various blood cell types. Many blood diseases, rare and common can and have been exploited using systems biology approaches with successful results and therefore ideal models for systems medicine. More importantly, hematopoiesis offers one of the best studied systems with insight into stem cell biology, cellular interaction, development; linage programing and reprograming that are every day influenced by the most mature and understood regulatory networks.

More books from Springer New York

Cover of the book Meyers' Dynamic Radiology of the Abdomen by
Cover of the book Atlas of Practical Mohs Histopathology by
Cover of the book Lipids and Women’s Health by
Cover of the book Adult Stem Cell Therapies: Alternatives to Plasticity by
Cover of the book Ionic Equilibria in Analytical Chemistry by
Cover of the book Ways of Knowing in HCI by
Cover of the book Imaging in CNS Drug Discovery and Development by
Cover of the book Bioarchaeology by
Cover of the book Behavioral Sciences by
Cover of the book Tissue Functioning and Remodeling in the Circulatory and Ventilatory Systems by
Cover of the book Reviews of Environmental Contamination and Toxicology by
Cover of the book Social Change and Personality by
Cover of the book Sleep Disorders Medicine by
Cover of the book Ultra High-Speed CMOS Circuits by
Cover of the book A Spectroscopic Atlas of Bright Stars by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy