A Historical Perspective on Evidence-Based Immunology

Nonfiction, Health & Well Being, Medical, Medical Science, Immunology, Science & Nature, Science
Cover of the book A Historical Perspective on Evidence-Based Immunology by Edward J. Moticka, Elsevier Science
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Author: Edward J. Moticka ISBN: 9780123983756
Publisher: Elsevier Science Publication: November 25, 2015
Imprint: Elsevier Language: English
Author: Edward J. Moticka
ISBN: 9780123983756
Publisher: Elsevier Science
Publication: November 25, 2015
Imprint: Elsevier
Language: English

A Historical Perspective on Evidence-Based Immunology focuses on the results of hypothesis-driven, controlled scientific experiments that have led to the current understanding of immunological principles. The text helps beginning students in biomedical disciplines understand the basis of immunologic knowledge, while also helping more advanced students gain further insights.

The book serves as a crucial reference for researchers studying the evolution of ideas and scientific methods, including fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, the generation of diversity and mechanism of tolerance of T cells and B cells, the first cytokines, the concept of autoimmunity, the identification of NK cells as a unique cell type, the structure of antibody molecules and identification of Fab and Fc regions, and dendritic cells.

  • Provides a complete review of the hypothesis-driven, controlled scientific experiments that have led to our current understanding of immunological principles
  • Explains the types of experiments that were performed and how the interpretation of the experiments altered the understanding of immunology
  • Presents concepts such as the division of lymphocytes into functionally different populations in their historical context
  • Includes fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, and the generation of diversity and mechanism of tolerance of T and B cells
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A Historical Perspective on Evidence-Based Immunology focuses on the results of hypothesis-driven, controlled scientific experiments that have led to the current understanding of immunological principles. The text helps beginning students in biomedical disciplines understand the basis of immunologic knowledge, while also helping more advanced students gain further insights.

The book serves as a crucial reference for researchers studying the evolution of ideas and scientific methods, including fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, the generation of diversity and mechanism of tolerance of T cells and B cells, the first cytokines, the concept of autoimmunity, the identification of NK cells as a unique cell type, the structure of antibody molecules and identification of Fab and Fc regions, and dendritic cells.

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